Treatment
  • DEFINITIVE
  • PALIATIVE
Definitive
 

RADIOTHERAPY

Has been used to treat axillar hyperhidrosis. High-dose radiation (rads) is necessary to treat hyperhidrosis. Such a dose causes serious dermatitis, fibrosis, skin retraction, ending with serious functional limitation of shoulder movements.

AXILLARY SWEAT GLAND ABLATION

An usual ellipsical area of skin and glandular tissue is removed from the armpit and the space is closed by Z-plasty. The results depend on the size of the area excised. Local chronic eczematous dermatitis, keloid formation and various late contractures may occur interfering with the abduction of the shoulder.

AXILLAR LIPOSUCTION

Liposuction surgery of the axillar vault doesn’t extract sweat glands. Its effect is questionable.

THORACIC ENDOSCPIC SYMPATHICOTOMY

This is the best method for the treatment of the hyperidrosis. Activation of the sweat glands is done by the sympathetic nervous system. When the stimulus to the gland is exaggerated, the result is excessive sweating.

Sympathicotomy for the treatment of palmar, axillary and facial hyperhidrosis consists of cutting at a certain points along the sympathetic chain, which is located on the inside of the thoracic cavity. This stops the stimulus to the sweat glands and the sweating disappears.

Dr. Peter Kux and his late uncle, Dr. E. Kux, pioneered the use of the endoscope for thoracic sympathicotomy in the 1940’s. This allows the operation to be done with 2 small punctures of the thoracic cavity, which is far less aggressive than the conventional technique of making large incisions in the thorax or neck. This technique, Thoracic Sympathicotomy via endoscope, has become the method of choice for the treatment of hyperhidrosis.

In 1992, with over 50 years of experience in the technique of endoscopic thoracic sympathicotomy, and over 6,000 surgeries performed, Dr. Kux teamed up with Dr. João Bosco Vieira Duarte to adapt the surgery to the video endoscope. To include the video, technical and tactical modifications were necessary. The procedure became even safer and the results were improved. The technique now used by the team treats excessive sweating of the hands, armpits and the face. The surgical procedure is done under general anesthesia through two incisions of 3 mm on each side of the thorax. It lasts about 30 minutes.

The results so far are 100% of patients cured of hyperhidrosis of the hands, 96% for the armpits and 99% for face. The results are immediate and definitive. For patients with hyperhidrosis of the feet in combination with hands, face or armpits, 94% have had the condition improved or cured completely. The surgery is performed on an outpatient basis. The patient is discharged the same day. There is no need to spend the night in the hospital. The recovery is quick and the patient can return to normal activities soon.In some cases, there is an increase of sweating in the abdominal and lumbar areas, which disappears in a few days. It is rarely persistent. Complications are rare with this method.

Paliative

ANTIPERSPIRANTS:

• Glutaraldehyde 10%: Acts directly on the sweat glands. A good clinical effect is obtained in 72 hours. Undesirable brown discoloration occurs on the skin. Patients dislike prolonged treatment for cosmetic reasons. After cessation of treatment, increased sweating gradually reappeared after five to seven days.

• 20% Aluminum Chloride Hexahydrate: The mechanism by Aluminum Chloride decreases sweating is not known. Its effect decreases over the months. Skin irritation may occur in up to 50% of the patients. Sweating comes back few days after stopping treatment. It doesn’t succeed in all patients.


IONTOPHORESIS

Consists, basically, of applying a filtered Galvanic current with standard wet-pad electrodes or waterbath trays. It has been used to treat palmar, axillar and plantar hyperhidrosis. The mechanism of production of anhidrosis by iontophoresis seems to be an interrupted stimulus-secretion-coupling which leads to a functional disturbance of sweat secretion. It is effective in about 70% of the patients treated. Initially, it is done daily until sufficient diminution in sweating has occurred. Afterwards, treatment should be repeated at intervals as needed to maintain sufficient dryness. A perfect contact between the machine and the skin is necessary to avoid islands of hyperhidrosis. Side effects of this method are discomfort, burning, tingling, and skin irritation with erythema and vesicles. Care is required to prevent electrical shock and skin burns.

Sweating returns after stopping the applications.

DRUGS

There are no specific drugs to treat hyperhidrosis. The drugs in the groups anticholinergis, psycotropics and beta-blockers can diminish sweating but the side effects are too great to use them for very long.